Syai · Applications

Prediabetes and metabolic health

70% of people with prediabetes don't know it. A 14-day CGM run is the fastest way to see how your body reacts to food and exertion.

Prediabetes and metabolic health
About the condition

What it is

Prediabetes — glucose above normal but below the T2D threshold: HbA1c 5.7-6.4% (ADA) or 6.0-6.4% (WHO), fasting 5.6-6.9 mmol/L, OGTT 7.8-11.1 mmol/L. Without intervention, 5-15% per year progress to T2D. Lifestyle (DPP trial) reduces risk by 58%.

Treatment

Principles

1

Risk-factor screening

Age > 45, BMI > 25 (>23 in Asian populations), sedentary lifestyle, family history of T2D, prior GDM.

2

Weight loss

5-7% of starting weight — effect on glycaemia confirmed by DPP. Weight maintenance matters more than speed of loss.

3

150 min of activity a week

Aerobic + resistance. At least 3 sessions a week.

4

CGM as an education tool

A single 14-day course shows the real glucose response to one's usual food. Often changes behaviour long-term without a prescription.

Syai's role

Syai's role

For prediabetes, a single 14-day sensor (or one every 3 months) is enough. The goal — see your food triggers, morning dawn phenomenon, stress response. The patient becomes their own metabolism researcher. No prescription needed in most jurisdictions.

Evidence

Studies

  1. Diabetes Prevention Program — 58% reduction in progression to T2D

    DPP Research Group · New England Journal of Medicine · 2002

  2. Use of CGM in prediabetes — behavioural and metabolic outcomes

    Ehrhardt N., Al Zaghal E. · Diabetes Spectrum · 2019

    On request

Further reading

More on the manufacturer's site

Syai Health maintains a detailed topic page with clinical cases. Opens in a new tab.