Syai · Applications

CGM in pregnancy

Any form of diabetes in pregnancy needs a tighter target range. CGM makes that achievable.

CGM in pregnancy
About the condition

What it is

Gestational diabetes (GDM) is diabetes first diagnosed in pregnancy. By IADPSG/WHO 2013 criteria the prevalence is 10-20% in most countries. Pre-existing T1D and T2D also fall under "diabetes in pregnancy". The goal is to minimise macrosomia, preeclampsia and neonatal hypoglycaemia risk.

Classification

Pregnancy-specific targets

  1. TIR

    Time in range 3.5–7.8 mmol/L > 70%. Tighter than non-pregnant adults.

  2. Fasting glucose

    < 5.3 mmol/L pre-meal and fasting.

  3. 1 h post-meal

    < 7.8 mmol/L per IADPSG criteria.

  4. 2 h post-meal

    < 6.7 mmol/L in diabetes in pregnancy.

  5. TBR

    Time below 3.5 mmol/L < 4%. Maternal hypos are a stressor on the fetus.

Treatment

Approach

1

Diagnosis by OGTT

Screen at 24-28 weeks with a 75 g OGTT. Early (first-trimester) screen for at-risk women.

2

Diet + physical activity

First line. 70–80% of GDM cases compensate with lifestyle and no insulin.

3

Insulin — the standard

If 1-2 weeks of diet is not enough. Metformin is an option in some protocols, but insulin remains first-line in most guidelines.

4

CGM from the moment insulin starts

CONCEPTT (Lancet 2017) showed a 50% drop in neonatal complications among CGM-using T1D pregnancies. Extension to GDM is in current guidelines.

Syai's role

Syai's role

Syai can be worn from diagnosis through delivery. MARD < 10% accuracy meets the insulin-dosing requirement for CGM in pregnancy. No finger-stick checks is a separate gain on top of the existing exam burden. Post-delivery, the same sensor screens for residual diabetes.

Evidence

Studies

  1. CONCEPTT — CGM in T1D pregnancy

    Feig D.S. et al. · The Lancet · 2017

  2. IADPSG diagnostic criteria for hyperglycemia in pregnancy

    International Association of Diabetes and Pregnancy Study Groups · Diabetes Care · 2010

    On request

Further reading

More on the manufacturer's site

Syai Health maintains a detailed topic page with clinical cases. Opens in a new tab.