iXell · Applications

Prediabetes and T2D prevention

Prediabetes is a window of opportunity. Lifestyle change in this period cuts T2D incidence by 58% (DPP). Periodic home readings are an inexpensive way to confirm the trend is heading the right way.

Prediabetes and T2D prevention
About the condition

Who qualifies

Per ADA 2024, prediabetes is defined by HbA1c 5.7–6.4%, fasting glucose 5.6–6.9 mmol/L, or 7.8–11.0 mmol/L 2 h post-OGTT. Any of the three is sufficient. Without intervention, 11–37% of patients with prediabetes progress to T2D within 5 years.

Treatment

What to do at the prediabetes stage

1

Fasting reading twice a month

Not every day — that's excess strain. Every two weeks fasting gives the trend. Aim for < 5.6 mmol/L.

2

Paired reading after a new dish

Curious how your body reacts to plov, shashlik, a birthday cake? Measure before-meal + 2 hours after. A safe way to learn your own glycemic response.

3

Lab HbA1c every 6 months

The glucometer shows daily values; HbA1c shows the long-term trend. They don't replace each other. Home readings are tactical monitoring; HbA1c is strategic.

4

Metformin — if prescribed

ADA recommends metformin for prediabetes in patients < 60 with BMI > 35 or a history of GDM. On metformin you don't need to change SMBG frequency — the drug doesn't cause hypoglycemia.

iXell's role

Minimal infrastructure investment

Prediabetes doesn't justify a CGM sensor and its consumables — measurement frequency is too low. An ISO-certified meter and a pack of 50 strips covers six months of preventive monitoring. iXell's 5-year warranty spans the entire critical window between prediabetes diagnosis and its outcome.

Evidence

References

  1. Diabetes Prevention Program — 58% T2D risk reduction via lifestyle

    Knowler W.C. et al. · New England Journal of Medicine · 2002

    On request
  2. ADA Standards of Care 2024 — prevention and prediabetes

    Diabetes Care · 2024

    On request